«Filler» is used for two things that are not alike: products that add volume from day one, and products that fill nothing at all but make your own body build collagen. Confusing them is where most disappointment starts.
The two families, and why the difference matters
Everything injected to add volume falls into one of two groups, and they work by different mechanisms:
- Hyaluronic acid (Juvéderm®, Restylane®). A gel that occupies space. The volume is there when you walk out. And — this is the decisive part — it is reversible: an enzyme, hyaluronidase, dissolves it within hours if you dislike the result or if a complication appears.
- Biostimulators (Sculptra®, Radiesse®). They do not fill: they leave a particle that triggers a controlled tissue response, and it is your own collagen that provides the volume over weeks. There is no enzyme to undo it.
Two rules follow, and they settle most decisions: in high-risk areas or in a first-time patient, hyaluronic acid wins because it is reversible; in diffuse loss of support across a hollowed mid-face, a biostimulator gives a more natural and longer-lasting result, at the price of patience and irreversibility.
The three products, compared
| Hyaluronic acid | Sculptra® | Radiesse® | |
|---|---|---|---|
| What it is | Cross-linked hyaluronic acid gel | Poly-L-lactic acid (PLLA) | Calcium hydroxylapatite (CaHA) |
| How it works | Occupies volume | Stimulates your own collagen | Immediate volume and stimulation |
| When you see it | Same day | At 3–6 months | Same day, and improves after |
| Sessions | One | 2–3, four to six weeks apart | One |
| How long it lasts | 6–18 months by area and product | Up to 2 years | 12–18 months |
| Reversible? | Yes, with hyaluronidase | No | Not with hyaluronidase |
| Lips | Yes | No | No |
| Manufacturer | Allergan (Juvéderm®) · Galderma (Restylane®) | Galderma | Merz |
No product is better than another: there is a right one per indication. A clinic that proposes the same thing for everything probably only stocks that.
The conversation almost nobody has: vascular risk
Filler has one serious, uncommon complication worth knowing about beforehand rather than after: vascular occlusion. If product enters an artery or compresses it, the territory that artery supplies loses its blood flow. It can end in skin necrosis and, in areas near the orbit, in vision loss.
It is uncommon, and it is why certain things are not negotiable:
- That hyaluronidase is in the clinic, that day. It is the antidote and its usefulness is measured in hours. Asking whether they have it is the single most useful question you can ask, and the one that most discomforts anyone who does not.
- That a physician injects, one who knows the vascular anatomy of the face.
- That the highest-risk areas — glabella, nose, tear trough and nasolabial folds — are treated with judgement and with a reversible product.
Signs that mean calling immediately: pain out of proportion during or after the injection, skin blanching, a purplish mottling, or any change in vision. None of these wait until morning.
How filler is quoted
Filler is not quoted by «area» but by product and volume, and for a reason worth understanding before you compare: two people with the same complaint can need 1 ml and 4 ml. A closed per-area price that does not say how many millilitres it includes cannot be compared with anything — the same problem as botox units.
How it works here:
- The consultation is free and is not charged in advance. You are assessed, told which product, how much volume and the total, and you decide then.
- The quote is given in writing with the brand, the batch number and the millilitres before anything is applied. That document is what makes comparison possible.
- You pay for what is applied. If your case needs less volume than expected, you pay less.
Payment: cash, debit card and credit card, with the option to split into instalments at the terminal under your own bank plan.
Frequently asked questions
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We assess the whole face before proposing a product or a volume.
WhatsApp+57 316 042 2194 · El Poblado, Medellín · English spoken
About who signs this content
Dr. Olga González — physician trained in Aesthetic Medicine (Universidad de San Martín), Health Coach in Nutrition, Longevity and Biohacking. She practises at Dra. Juventud, El Poblado, Medellín. Consultations available in English.
Last reviewed: September 1, 2026