Complete guide

Collagen biostimulators
in Medellín

What each product does, which area it belongs in, and the questions to ask before anyone injects you.

Written and reviewed by Dra. Olga González · Aesthetic Medicine, Universidad de San Martín · Medellín, Medellín
Last reviewed: September 1, 2026

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On this page

  1. The two families
  2. The two products
  3. Vascular risk
  4. How it is quoted

«Filler» is used for two things that are not alike: products that add volume from day one, and products that fill nothing at all but make your own body build collagen. Confusing them is where most disappointment starts.

Comparative diagram of the two filler families: hyaluronic acid that adds immediate volume and biostimulators Sculptra and Radiesse that stimulate the body’s own collagen
The two families. Hyaluronic acid fills and is reversible; biostimulators do not fill — they make your body produce collagen.

The two families, and why the difference matters

Everything injected to add volume falls into one of two groups, and they work by different mechanisms:

Two rules follow, and they settle most decisions: in high-risk areas or in a first-time patient, hyaluronic acid wins because it is reversible; in diffuse loss of support across a hollowed mid-face, a biostimulator gives a more natural and longer-lasting result, in exchange for patience and irreversibility.

This practice works with biostimulators only: Sculptra® and Radiesse®. Hyaluronic acid is not offered, and that includes lips and cheeks. We say it up here rather than in the small print because it changes who this page is useful to.

If your assessment concludes that hyaluronic acid is what your case needs, you will be told so and referred. That is better than proposing what happens to be in stock.

The two products, compared

Sculptra®Radiesse®
What it isPoly-L-lactic acid (PLLA)Calcium hydroxylapatite (CaHA)
How it worksStimulates your own collagenImmediate volume and stimulation
When you see itAt 3–6 monthsSame day, and improves after
Sessions2–3, four to six weeks apartOne
How long it lastsUp to 2 years12–18 months
Reversible?NoNo
Price$2,400,000 COP per session$2,200,000 COP per session
ManufacturerGaldermaMerz

Neither is undone by an enzyme, and neither is used in lips. If what you want is immediate, reversible volume, that is hyaluronic acid and it is not offered here.

Between the two the choice is not about price: Radiesse gives volume the same day and is done in one session; Sculptra takes months and needs two or three, but lasts longer and the result is your own collagen.

The conversation almost nobody has: vascular risk

Filler has one serious, uncommon complication worth knowing about beforehand rather than after: vascular occlusion. If product enters an artery or compresses it, the territory that artery supplies loses its blood flow. It can end in skin necrosis and, in areas near the orbit, in vision loss.

It is uncommon, and it is why certain things are not negotiable:

Signs that mean calling immediately: pain out of proportion during or after the injection, skin blanching, a purplish mottling, or any change in vision. None of these wait until morning.

How it is quoted

TreatmentPriceApprox. USD
Sculptra®$2.400.000USD 747per session
Radiesse®$2.200.000USD 685per session

2026 rate · Dr. Olga González, Medellín, Medellín. Free consultation. Dollar figures are approximate and move with the exchange rate.

Biostimulators are not quoted by millilitres but per session, and the figure above is the final price of the session. It is easier to compare than a hyaluronic acid filler, where a per-area price means nothing unless it states how many millilitres it includes.

How it works here:

Payment: cash, debit card and credit card, with the option to split into instalments at the terminal under your own bank plan.

Frequently asked questions

?What is the difference between a filler and a biostimulator?
A hyaluronic acid filler is a gel that occupies volume: the result is there the same day and it can be dissolved with hyaluronidase. A biostimulator such as Sculptra or Radiesse does not fill — it makes your own body produce collagen, takes weeks or months to show, and cannot be reversed with an enzyme.
?How long does dermal filler last?
Hyaluronic acid lasts 6 to 18 months depending on area and product: less in the lips, which move constantly, and more in the cheeks. Radiesse lasts 12 to 18 months and Sculptra up to two years.
?Does it hurt?
The syringes contain anaesthetic and topical cream is applied beforehand. Most people describe it as uncomfortable rather than painful. The lips are the most sensitive area.
?Can it be removed if I do not like it?
Hyaluronic acid can, with hyaluronidase, and the effect shows within hours. Sculptra and Radiesse do not dissolve with that enzyme, which is why starting with a reversible product is sensible if it is your first time.
?Can it be combined with botox or Ultraformer?
Yes, and it usually is: toxin relaxes muscle, filler restores volume and Ultraformer MPT works on SMAS laxity. Three different problems. The order and intervals are set at the consultation.

Book a free consultation

We assess the whole face before proposing a product or a volume.

WhatsApp

+57 316 042 2194 · Medellín, Medellín · English spoken

About who signs this content

Dr. Olga González — physician trained in Aesthetic Medicine (Universidad de San Martín), Health Coach in Nutrition, Longevity and Biohacking. She practises at Dra. Juventud, Medellín, Medellín. Consultations available in English.

Last reviewed: September 1, 2026

Medical notice. This page is informational and does not replace the judgement of a healthcare professional. Fillers and biostimulators are prescription devices and medicines: the indication, product and volume depend on an individual assessment. Results vary from person to person and nothing here is a promise of outcome. Market price ranges are those publicly observed in Medellín in 2026 and are not official third-party rates. Dollar figures are approximate.